Recent studies have shown that CBD can help prevent the onset of diabetes. It has also been shown to help prevent or better cope with some of the complications that arise out of diabetes.
The best CBD oil for helping prevent and treat diabetes is a tincture taken daily via the mouth. A few drops under the tongue, daily, can make a big difference.
Diabetes affects 8.5% of the population worldwide. It is a lifelong condition that can be controlled through medication, diet, lifestyle, and exercise. With proper management, sufferers can lead long, healthy lives without complications. However, those who do not control it effectively or who face unexpected complications can face serious consequences, including illness, blindness, amputations, and death. Research linking CBD oil to diabetes is exciting, as it could provide an easier, more effective way of living with the condition.
It can be easy to judge from the outside, but proper management of diabetes is far from easy. Adults who are diagnosed have to make significant life changes, which require a lot of discipline and attention, and can lead to anxiety and panic.Children and teenagers who suffer from diabetes do not always understand the consequences of reckless eating and not living a healthy lifestyle.
Furthermore, people in low socioeconomic households or in third world countries do not always have the luxury of choosing healthy eating options. They may also not have enough time to exercise on a daily basis.
Diabetes: Type 1 & Type 2
Before we go into just how CBD can help people with diabetes, let’s take a quick refresher on the two types of diabetes:
- Type 1 diabetes is found in only 5% of diabetes sufferers. It usually starts during childhood, and is caused by the body’s immune system destroying the cells that produce insulin.
- Type 2 diabetes usually develops in adulthood, and can be prevented by diet and lifestyle. It is caused by the body’s inability to use insulin in the right way, otherwise known as insulin resistance.
Insulin is necessary for the cells to absorb sugar (glucose), without which they cannot produce energy.
Diabetes and CBD oil
CBD may have two roles in treating diabetes. Firstly, evidence indicates that it might prevent diabetes. Secondly, CBD can treat people with diabetes, improving overall health and preventing common complications.
Some of the most poignant evidence that CBD and other cannabis compounds may help prevent diabetes comes from data showing lower rates of diabetes in marijuana users. Of course, this does not necessarily point to CBD, and correlation does not imply causation. However, in tests performed on rats and mice, CBD was found to prevent the onset of diabetes. In people diagnosed as pre-diabetic, it is therefore recommended to use CBD as part of a healthier lifestyle.
With regards to the treatment and prevention of complications associated with diabetes, research into CBD has produced significant results. Diabetic retinopathy – a leading cause of blindness among adults, and which is notoriously difficult to treat – can be treated with CBD. This is because inflammation plays an important role in diabetic retinopathy, and CBD has extensive anti-inflammatory properties.
Finally, CBD is known to be effective in treating chronic neuropathic pain. Diabetes often causes this pain. Furthermore, CBD reduces oxidative stress, which is one of the risk factors for diabetes in the first place.
Who should use CBD for diabetes?
Since evidence indicates that CBD oil can help prevent diabetes, pre-diabetics and others who are at risk of contracting the condition should use it regularly.
People already suffering from diabetes should use CBD to maintain a healthy and balanced lifestyle, as well as treating pain and preventing complications.
CBD for Diabetes: Treatment for Disease and Symptoms
In the recent years, numerous cannabis researches are being conducted so as to find its said health benefits. In all these researches conducted, it has been said that cannabis has many significant effects in various diseases including diabetes. There are millions of people that are affected by diabetes across the world.
With researches and studies conducted saying that cannabis has significant positive effect in treatment and control of the disease, it is truly an interesting subject. Well then, what are these said positive effects of CBD for diabetes? How does Cannabidiol help patients suffering from the different symptoms of diabetes?
Studies in mice have shown that the incidence of diabetes in non-CBD-treated mice was significantly reduced from 83% to 30% when treated with CBD. Treatment with CBD also shows a significant reduction in plasma levels of proinflammatory cytokines (IFN-gamma and TNF-alpha.)
The production of Th1-associated cytokine from in vitro activated T cells and peritoneal macrophages was also significantly reduced in the mice treated with CBD. While the production of IL-4 and IL-10 (Th2-associated cytokines) was increased compared to mice not treated with CBD.
The histological examination of CBD-treated mice on the pancreas showed significantly reduced insulitis. Source : https://www.ncbi.nlm.nih.gov/pubmed/16698671
Diabetes is connected with high levels of the fasting insulin, insulin resistance and low levels of high-density lipoprotein cholesterol (HDL-C). In the past year, a study on cannabis’s effects on fasting insulin and insulin resistance shows that cannabis users have lower fasting insulin levels.
This is compared to those that have never used cannabis before. In addition, those who have used cannabis long before but is not current users have similar but less pronounced low level fasting insulin. This indicates that the cannabis’ protective effect fades after some time.
Excluding diabetics, researches still found that current cannabis users have reduced levels of insulin resistance and fasting insulin. This shows that not only cannabis helps in controlling the symptoms of diagnosed diabetics but also in preventing its occurrence in the first place.
When cells start to reject the body’s normal mechanism known as insulin, it is a condition called insulin resistance or IR.
Insulin is a hormone produced by pancreas and is essential in regulating glucose metabolism.
Insulin resistance is linked with Type 2 diabetes where the insulin production is not affected, the cells cannot process it.
With the cells becoming resistant to insulin, they become unable to absorb glucose which is needed in supplying the body with energy. When the unused glucose in the bloodstream builds up, this eventually leads to development of hyperglycemia. In the recent studies on CBD for diabetes, it has been found that cannabis users have blood glucose in significantly low levels compared to cannabidiol non users.
As a result of the disease, patients often experience nerve disorders.
The nerve damage induced by diabetes often affects the extremities such as hands and feet.
But they may also affect any organ or in any region of the body.
Diabetes’s nerve damage can be symptomless but in most cases, there is pain, numbness and tingling that accompanies it.
Treating diabetic neuropathy with conventional analgesics can be difficult. However, evidences were found that cannabis might also help in the treatment of diabetes-induced nerve damage. Cannabidiol extracts comes with pain-reducing effects and this was shown to have pronounced effect in neuropathy induced by diabetes.
In the study conducted related to CBD for diabetes and neuropathy, it seems like repeated administration has positive effect on mechanical allodynia and was also found to restore normal pain perception. CBD was found to have positive effects on nerve pain, protecting the liver from oxidative stress and restoring nerve growth factor back to normal levels.
Weight gain and obesity are both connected to diabetes risks. As obesity is associated with diabetes, many studies on cannabis’s effects on weight gain has been conducted. But these studies all have conflicting results that has made it difficult to establish how cannabis can help with diabetes in relation to weight gain.
However, a recent study shows that after being exposed to organic cannabis extract, obese rats lost weight significantly as well as gained an increase in pancreas’ weight. This shows that the presence of cannabinoids protect the beta cells of pancreas. This may help in controlling the disease as an autoimmune response destroys beta cells in type 1 diabetes.
Majority of diabetics acquire diabetic retinopathy after a long time of struggling with the disease. Diabetic retinopathy (DRP) is a complication wherein the cells of the retina become progressively damaged over time. The complication is related with breakdown of the blood-retinal barrier in the eyes preventing substances in the blood to enter the retinal tissue.
The breakdown of the retinal barrier is induced by glucose and is the cause for the neural tissue becoming exposed to neurotoxins. In addition, the blood-retinal barrier’s breakdown increases the chance of retinal bleeding. There is evidence found that cannabidiol can help in diabetes retinopathy as it is capable of combating inflammation and oxidative stress.
Both of these play a role in retinal cells’ breakdown. In the studies conducted in the relationship of diabetic retinopathy and cannabis, the results were quite positive in showing that cannabis is capable of significantly reducing neurotoxicity as well as oxidative stress. With that, the death of retinal cells as well as blood-retinal barrier’s breakdown can very well be prevented.
Other resources and links
- The impact of marijuana use on glucose, insulin, and insulin resistance among US adults
- CBD attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy
- CBD lowers incidence of diabetes in non-obese diabetic mice
- Neuroprotective and blood-retinal barrier-preserving effects of CBD in experimental diabetes
- Cannabidiol arrests onset of autoimmune diabetes in NOD mice
- Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation
- Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes
- The endocannabinoid system in obesity and type 2 diabetes
- Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
- The endocannabinoid system and plant-derived cannabinoids in diabetes and diabetic complications
- Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain
- Biochemical and immunohistochemical changes in delta-9-tetrahydrocannabinol-treated type 2 diabetic rats
- Efficacy and Safety of CBD and THC-V on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes